Development Resources

Appraisal of Guidelines Research and Evaluation (AGREE)
AGREE is an international collaboration of researchers and policy makers who work together to improve the quality and effectiveness of clinical practice guidelines by establishing a shared framework for their development, reporting and assessment. 

 Patient, Intervention, Comparison, Outcome (PICO)
Developing clinical questions (Presented by McMaster University) 

 Grading of Recommendations Assessment, Development and Evaluation (GRADE)
A systematic approach to grading the strength of management recommendations can minimize bias and aid interpretation of expert-created medical guidelines. The IDSA began to employ the use of the GRADE system in new guidelines and guideline updates initiated after October 2008. 
  

GRADE Online Learning Modules (presented by McMaster University) 

• Introduction to GRADE and Summary of Findings 
• Choosing a comparison and outcomes for the Summary of Findings Table 
• Assessing Risk of Bias 
• Assessing Inconsistency 
• Assessing Indirectness    
• Assessing Imprecision    
• Assessing Publication Bias 
• Assessing Other factors and upgrading 
• Using GRADEpro (60 minute demonstration)
• Download GRADEpro  
• Steps to creating Summary of Finding (SoF Tables) 

GRADE Strength of Recommendations and Quality of the Evidence Table