This course is the product of a collaboration between six highly-esteemed institutions: Brown University, Johns Hopkins University, University of Maryland, University of Pennsylvania, UT Southwestern Medical Center and Washington University in St. Louis. At its inception more than two decades ago, the course was a small and simple collaboration of field experts and their own trainees. Now in its 21st year, the course has gained national renown and attracts participants from all across the United States. This three-day training course offers an interactive series of sessions on basic healthcare epidemiology, infection prevention strategies, healthcare-associated infections and problem pathogens. This course includes didactic lectures and panel discussions with world-renowned faculty from various specialties. The course meets requirements for Infectious Disease fellows for course work in healthcare epidemiology and infection prevention as outlined by the American Board for Internal Medicine.