Skip to nav Skip to content

Guideline Development Process

Facebook Twitter LinkedIn Email

Appraisal of Guidelines Research and Evaluation (AGREE)
AGREE is an international collaboration of researchers and policy makers who work together to improve the quality and effectiveness of clinical practice guidelines by establishing a shared framework for their development, reporting and assessment.

IDSA Handbook on Guideline Development

Grading of Recommendations Assessment, Development and Evaluation (GRADE)
A systematic approach to grading the strength of management recommendations can minimize bias and aid interpretation of expert-created medical guidelines. The IDSA began to employ the use of the GRADE system in new guidelines and guideline updates initiated after October 2008. 

GRADE Online Learning Modules (presented by McMaster University)

GRADE Strength of Recommendations and Quality of the Evidence Table


Patient, Intervention, Comparison, Outcome (PICO)
Developing clinical questions (Presented by McMaster University)

This website uses cookies

We use cookies to ensure that we give you the best experience on our website. Cookies facilitate the functioning of this site including a member login and personalized experience. Cookies are also used to generate analytics to improve this site as well as enable social media functionality.