Misinformation about COVID-19, including vaccines, treatments and the government’s role, has been fueling vaccine hesitancy. In this episode, IDSA President Dr. Daniel McQuillen, FIDSA, IDSA President-Elect Dr. Carlos del Rio, FIDSA and John Bridgeland, co-founder and CEO of the COVID Collaborative, discuss what is being done to combat misinformation, how to address myths with vaccine hesitant patients, the impact misinformation has on the future of medicine and the latest information on omicron.