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Therapeutics Under Early Investigation

Last updated: February 24, 2021

The following is a curated review of key information and literature about this topic. It is not comprehensive of all data related to this subject.

Overview

There are many therapeutics under early investigation for treatment of COVID-19 for which there is currently insufficient clinical data to recommend either for or against. This overview is not a comprehensive summary, but a list of therapeutics with strong biological plausibility that are available in the United States and are or will be studied by clinical trial.

Theraputics Under Investigation pic.png

*Published clinical studies (including preprints). Excludes case reports and case series.

Resources

ACTIV Trials Directory

This NIH directory lists master protocols and information about individual clinical trials within the ACTIV therapeutic development partnership.

VISIT WEBSITE

WHO’s Solidarity Clinical Trial Adds Three New Candidate Drugs

Solidarity PLUS will enroll hospitalized patients to test artesunate, imatinib and infliximab, according to this World Health Organization announcement.

VISIT WEBSITE

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

In critically ill patients, therapeutic-dose anticoagulation with heparin did not result in greater probability of survival to hospital discharge or a greater number of days free of cardiovascular or respiratory organ support.

VISIT WEBSITE

FDA Coronavirus Treatment Acceleration Program Dashboard

This page provides a snapshot of potential COVID-19 therapeutics by category and stage of progress that are being developed through FDA’s CTAP.

VISIT WEBSITE

Multimedia

CDC/IDSA COVID-19 Clinician Call: COVID-19 Treatment Updates

Experts discuss anti-SARS-CoV-2 monoclonal antibodies for treatment and prevention, ivermectin and the data underlying recommendations against its use, and recent findings on fluvoxamine as a therapy under investigation.

PLAY MEDIA

Society of Infectious Diseases Pharmacists Video Briefing: Colchicine

An SIDP COVID-19 Therapeutic Review of colchicine for COVID-19.

PLAY MEDIA
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