Charles Holmes, MD, MPH, is founder and director of the Georgetown Center for Innovation in Global Health; professor of medicine and distinguished scholar at the O’Neill Institute for National and Global Health Law at Georgetown University; and adjunct clinical faculty at Johns Hopkins. Dr. Holmes is an accomplished global health leader, diplomat and clinician-scientist with executive experience recruiting and leading a diverse workforce toward public health and development goals. He is widely published in the research and policy literature and leads a portfolio of health innovation programs in multiple countries. He previously served as chief medical officer and a deputy U.S. global AIDS coordinator for the $6.5 billion U.S. President’s Emergency Plan for AIDS Relief, where he led teams supporting innovative initiatives during the Obama-Biden Administration and developed and defended U.S. government budgets and policies. He subsequently led a team that transformed a 1,000-person Zambian health organization into a model of governance, public health effectiveness and local ownership over four years, resulting in more than $150 million in funding and substantial growth in research and training productivity and public health impact. He is a member of the Council on Foreign Relations and served on the Biden-Harris Transition (Agency Review Team) for International Development.